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FACULTY 교수진

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교수진 소개

신주호조교수 / Prof. Jooho Shin jshin24@skku.edu http://biomed.skku.edu/jhshin

  • 소속
    약리학 분과
  • 연구실명
    신경재생연구실
  • 전공분야
    퇴행성 뇌질환
  • Location
  • Phone
    031-299-6192
  • FAX
    031-299-6209

연구소개

학력 및 경력

2012.03 – 현재

성균관대학교 의과대학 조교수

2006.08 – 2012.02

Postdoctoral fellow, Johns Hopkins University (Ted M. Dawson M.D./Ph.D.)

2005.12 – 2006.04

Postdoctoral researcher, University of Vienna, (Gert Lubec Ph.D.)

2003.02 – 2005.12

Ph.D. in chemistry, University of Vienna, (Gert Lubec Ph.D.)

2001.03 – 2003.02

서울대학교 의과대학 석사 (종양생물학, Jae-Gahb Park M.D./Ph.D.)

1994.03 – 1998.02 

서울대학교 농업생명과학대학 동물자원과학과 학사

최근 연구 업적

  1. Ko HS, Bailey R, Smith WW, Liu Z, Shin JH, Lee YI, Zhang YJ, Jiang H, Ross CA, Moore DJ, Patterson C, Petrucelli L, Dawson TM, Dawson VL. CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. Proc. Natl. Acad. Sci. USA. 2009 Feb 24;106(8):2897-2902.
  2. Shin JH, Dawson VL, Dawson TM. SnapShot: pathogenesis of Parkinsons disease. Cell 2009 Oct 16;139(2):440.e1-2.
  3. Lee BD, Shin JH, Vankampen J, Petrucelli L, West AB, Ko HS, Lee YI, Maguire-Zeiss KA, Bowers WJ, Federoff HJ, Dawson VL, Dawson TM. Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinsons disease. Nat. Med. 2010 Sep;16(9): 998-1000.
  4. Ko HS, Lee Y, Shin JH, Karuppagounder SS, Gadad BS, Koleske AJ, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM. Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkins ubiquitination and protective function. Proc. Natl. Acad. Sci. USA. 2010 Sep 21;107(38):16691-16696.
  5. Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, Troncoso JC, Dawson VL, Dawson TM. PARIS (ZNF746) Represses PGC-1α Contributing to Neurodegeneration in Parkinsons Disease. Cell 2011 Mar 4;144(5):689-702.
  6. Zhang J, Wang Y, Chi Z, Keuss MJ, Pai YME, Kang H, Shin JH, Bugayenko A, Wang H, Xiong Y, Pletnikov MV., Mattson MP, Dawson TM., Dawson VL. Thorase (NPG6), A Novel AAA+ ATPase, Regulates AMPA Receptor-Dependent Synaptic Plasticity and Behavior. Cell 2011 15;145(2):284-99.
  7. Kang HC, Lee YI, Shin JH, Andrabi S, Chi Z, Gagne JP, Lee Y, Ko HS, Lee BD, Poirier G, Dawson VL, Dawson TM. Iduna is a Poly (ADP-Ribose) (PAR)-Dependent E3 Ubiquitin Ligase that Regulates DNA Damage. Proc. Natl. Acad. Sci. USA. 2011 23;108(34):14103-8